產(chǎn)品編號 | bs-6686R-Gold |
英文名稱1 | Rabbit Anti-ICAM5/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的細(xì)胞間粘附分子5抗體 |
別 名 | ICAM5_HUMAN; ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞類型標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 97kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ICAM5 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. Similarity: Belongs to the immunoglobulin superfamily. ICAM family. Contains 9 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: Q9UMF0.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |