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Mouse Anti-human CD274 (B7-H1, PD-L1)  antibody (bsm-30139M)
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说明书: 100ug  200ug  
100ug/1880.00元
200ug/5600.00元
大包装/询价

产品编号 bsm-30139M
英文名称 Mouse Anti-human CD274 (B7-H1, PD-L1)  antibody
中文名称 人CD274 (B7-H1, PD-L1)单克隆抗体
别    名 Programmed cell death 1 ligand 1; CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed death ligand 1; RGD1566211.  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 4C11
交叉反应 Human
产品应用 Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 32kDa
检测分子量 40
性    状 Liquid
亚    型 IgG1
纯化方法 affinity purified by Protein G
缓 冲 液 0.01M PBS (pH7.4).
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 TThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

SWISS:
Q9NZQ7

Gene ID:
29126

产品图片
Blank control(black line):MDA-MB-231. Primary Antibody (green line): Mouse Anti-Human PD-L1 antibody (bsm-30139M) Dilution:1ug/Test; Secondary Antibody(white blue line): Goat anti-mouse IgG-FITC Dilution: 0.5ug/Test. Isotype control(orange line): Normal Mouse IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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