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Rabbit Anti-CTR1  antibody (bs-10773R)  
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產(chǎn)品編號 bs-10773R
英文名稱 Rabbit Anti-CTR1  antibody
中文名稱 銅離子轉運蛋白1抗體
別    名 Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 (copper tansporters) member 1; Solute carrier family 31 member 1.  
研究領域 神經(jīng)生物學  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CTR1: 51-150/190 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]

Function:
High-affinity, saturable copper transporter involved in dietary copper uptake.

Subunit:
Homotrimer.

Subcellular Location:
Cell membrane. Localizes to the apical membrane in intestinal epithelial cells.

Post-translational modifications:
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.

Similarity:
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.

SWISS:
O15431

Gene ID:
1317

Database links:

Entrez Gene: 1317 Human

Entrez Gene: 20529 Mouse

Entrez Gene: 171135 Rat

Omim: 603085 Human

SwissProt: O15431 Human

SwissProt: Q8K211 Mouse

SwissProt: Q9JK41 Rat

Unigene: 532315 Human

Unigene: 248637 Mouse

Unigene: 2789 Rat



產(chǎn)品圖片
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CTR1 Polyclonal Antibody, Unconjugated(bs-10773R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
araformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTR1) Polyclonal Antibody, Unconjugated (bs-10773R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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