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Rabbit Anti-FAM5C  antibody (bs-16008R)
~~~促销代码KT202410~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-16008R
英文名称 Rabbit Anti-FAM5C  antibody
中文名称 FAM5C蛋白抗体
别    名 B830045N13Rik; BMP/retinoic acid inducible neural specific protein 3; BRINP3; BRNP3_HUMAN; DBCCR1 like protein 1; DBCCR1L; DBCCR1L1; Family with sequence similarity 5, member C; MGC107461; MGC40674; OTTMUSP00000028549; Protein FAM5C; RP11-445K1.1; RP23-212I24.1.  
研究领域 细胞生物  交换蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Chicken,Dog)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 85kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAM5C: 681-766/766 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 FAM5C belongs to the FAM5 family.

Function:
Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.

Subcellular Location:
Secreted

Tissue Specificity:
Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.

Similarity:
Belongs to the BRINP family.
Contains 1 MACPF domain.

SWISS:
Q76B58

Gene ID:
339479

Database links:

Entrez Gene: 339479 Human

SwissProt: Q76B58 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM5C) Polyclonal Antibody, Unconjugated (bs-16008R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM5C) Polyclonal Antibody, Unconjugated (bs-16008R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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