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Rabbit Anti-FRMD5  antibody (bs-8237R)  
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產品編號 bs-8237R
英文名稱 Rabbit Anti-FRMD5  antibody
中文名稱 FRMD5蛋白抗體
別    名 FERM domain containing 5; FERM domain-containing protein 5; FLJ41022; FRMD5; FRMD5_HUMAN; MGC14161.  
研究領域 細胞生物  免疫學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRMD5: 211-312/570 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD5 (FERM domain-containing protein 5) is a 570 amino acid single-pass membrane protein that contains one FERM domain and exists as two alternatively spliced isoforms. The gene encoding FRMD5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Similarity:
Contains 1 FERM domain.

SWISS:
Q7Z6J6

Gene ID:
84978

Database links:

Entrez Gene: 84978 Human

Entrez Gene: 228564 Mouse

Entrez Gene: 311362 Rat

SwissProt: Q7Z6J6 Human

SwissProt: Q6P5H6 Mouse

Unigene: 578544 Human



產品圖片
Sample: HepG2 (human)cell Lysate at 40 ug U937 (human)cell Lysate at 40 ug Primary: Anti-FRMD5 (bs-8237R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 65 kD Observed band size: 63 kD
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