產品介紹 |
Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
胰島淀粉樣肽(islet amyloid polypeptide,IAPP)又稱amylin 或糖尿病相關肽是由胰腺β細胞產生的一種短肽。IAPP降低胰島素的敏感性,抑制肌肉組織中葡萄糖的攝取和糖原的合成,抑制病人攝取食物
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