| 产品编号 | bs-3615R |
| 英文名称 | Rabbit Anti-ESM1 antibody |
| 中文名称 | 内皮细胞特异性分子1抗体 |
| 别 名 | Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1. |
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Specific References (3) | bs-3615R has been referenced in 3 publications.
[IF=8.897] Wu, Qingsi. et al. Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment. Nano Res. 2021 Dec;:1-13 IF ; Mouse.
[IF=4.522] Zhao H et al. miR‐181a/b‐5p ameliorates inflammatory response in monocrotaline‐induced pulmonary arterial hypertension by targeting endocan. J Cell Physiol. 2019 Oct 21. IHF&ICF ; Rat.
[IF=0] Farahlina Baba. et al. Endocan-microvascular Density in Primary Ovarian Carcinoma. Asian Pac J Cancer P. 2022 Mar 1;23(3):929-935 IHC ; Human.
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| 研究领域 | 心血管 免疫学 细胞粘附分子 内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Mouse,Rat,Pig,Cow,Horse) |
| 产品应用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 20kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ESM1: 51-150/184 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. Function: May have potent implications in lung endothelial cell-leukocyte interactions. Subunit: Monomer. Subcellular Location: Secreted. Peroxisome. Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. Post-translational modifications: May contain intrachain disulfide bonds. Similarity: Contains 1 IGFBP N-terminal domain. SWISS: Q9NQ30 Gene ID: 11082 Database links: Entrez Gene: 11082 Human Entrez Gene: 71690 Mouse Omim: 601521 Human SwissProt: Q9NQ30 Human SwissProt: Q9QYY7 Mouse Unigene: 129944 Human Unigene: 38929 Mouse |
| 产品图片 |
Sample:
Lane 1: Human HUVEC cell lysates
Lane 2: Human U-2 OS cell lysates
Lane 3: Human A549 cell lysates
Primary: Anti-ESM1 (bs-3615R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 43-47 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
