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Rabbit Anti-CTNNAL1  antibody (bs-1685R)  
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產品編號 bs-1685R
英文名稱 Rabbit Anti-CTNNAL1  antibody
中文名稱 粘附分子相關蛋白a1抗體
別    名 ACRP; Alpha catenin related protein; alpha CATU; Alpha catulin; alpha2 catulin; catenin (cadherin associated protein), alpha like 1; Catenin alpha like protein 1; catenin, alpha like 1; CLLP; Highly similar to ALPHA CATENIN; CTNL1_HUMAN; Alpha-catulin; Alpha-catenin-related protein; Catenin alpha-like protein 1.  
研究領域 免疫學  細胞膜受體  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 81kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CTNNAL1: 151-250/743 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms.

Function:
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).

Subunit:
Interacts with ARHGEF1.

Subcellular Location:
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.

Tissue Specificity:
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.

Similarity:
Belongs to the vinculin/alpha-catenin family.

SWISS:
Q9UBT7

Gene ID:
8727

Database links:

Entrez Gene: 8727 Human

Omim: 604785 Human

SwissProt: Q9UBT7 Human

Unigene: 58488 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTNNAL1) Polyclonal Antibody, Unconjugated (bs-1685R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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